I have a 2xxbee s2b one coordinator and one router so I want to know if there is a way that can I receive from receiver an ack that tells me that reciever recieve data from transmitter?
In API mode you can use API Frame 0x8B (Transmit Status).
There are some complications due to the nature of a ZigBee network. Esepcially in poor RF environments the indication could be misleading. See linked discussions for more information.