realport version and port ts 16 firmware version

We would like to use WS2008R2 (VM Guest) with the following version with Portserver TS16:
− Digi TS POST 82000685_G
− Digi TS firmware 82000684_V (although W is the latest release)
− Digi Realport driver 4.4.365.0 (although 4.5.373.0 is the latest release)

Is this recommended?

It is always recommended the latest versions are used in an effort to avoid running into any fixed bugs. You might want to look over the release notes to determine whether there is anything that has been fixed which may impact your particular deployment. If not, then there is no reason you couldn’t use the older version.