Are there any issues with running an FTDI Virtual COM Port over an AnywhereUSB?

I’m using FTDI VCP to provide a virtual COM port on an AnywhereUSB/2 hub. This works fine.

However, when the AnywhereUSB port is connected it disrupts communication on other FTDI VCPs running over real (hardware) USBs. Disconnect the Anywhere USB port and the problem goes away.

Has anyone encountered this?

Can anyone help on this one?