Can xbee ZB module is communicate with CC2650 sensor tag

XBee & XBee Gateway XBee - Zigbee
2

If you load the proper code on your 3rd party CC2650 and then set the XBee ZB module for Zigbee pro (ZS2), I don’t see why it would not work.

3

Xbee-S2C with Coordinator API firmware, Yes it works
Set same channel, on both side
In XCTU- Set CE- Enabled (1)
ZS- 2
DH- O
DL- FFFF
Set API enabled - API enabled without escape mode